Allergic asthma is the most common form of asthma. It affects people of all ages. As the name implies, it is triggered by allergens—substances that cause...
Read More »Scientists Take Major Step Toward Angelman Syndrome Gene Therapy
Babies born with a faulty maternal copy of the UBE3A gene will develop Angelman syndrome, a severe neurodevelopmental disorder with no cure and limited treatments. Now, for the first time...
Read More »APIS Assay Technologies and Moffitt Cancer Center sign Master Collaboration Agreement on lncRNA TROLL Biomarker assessment
APIS Assay Technologies Ltd. has entered into a Research & Development agreement with the Laboratory of Elsa Flores, Ph.D., and Marco Napoli, Ph.D. characterising the suitability of TROLL-2 and TROLL-3 as predictive biomarkers of cancer progression...
Read More »Novel CRISPR-assisted method detects RNA-binding proteins in living cells
While scientists still don’t fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding...
Read More »Collaborative research sheds light on ‘dark’ portion of genome
Just as there is a mysterious dark matter that accounts for 85 percent of our universe, there is a “dark” portion of the human genome that has perplexed scientists for decades. A study published March 9, 2020, in Genome Research identifies new portions of the fruit fly genome that, until now, have been hidden in these dark, silent areas. The ...
Read More »Novel role for a lncRNA molecule found in the blood vessel wall may have implications for chronic vascular disease states and aging
Investigators from Brigham and Women’s Hospital have made a potentially exciting discovery by jumping into the abyss of the dark side of the genome. Once dismissed as “junk DNA,” roughly 75 percent of the human genome do not code for proteins. But these dark regions of the genome are far from junk — instead, they may hold tantalizing clues about ...
Read More »Phantom genes keep diabetes at bay
Unlike what we commonly refer to as 'genes', these phantom genes or 'Long noncoding RNA' (LncRNAs) do not lead to the production of proteins that our cells, and thus our entire bodies are made of...
Read More »lncRNA that suppresses melanoma tumors has been identified
A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumour growth. Although the research is at an early stage, the team hope that their work could help develop new ways to combat melanoma and potentially other cancers too. The team from the University ...
Read More »Scientists image heart lncRNA structure for the first time
Scientists at Los Alamos and international partners have created the first 3-D images of a special type of RNA molecule that is critical for stem cell programming and known as the “dark matter” of the genome. “As far as we know,” said corresponding author Karissa Sanbonmatsu, “this is the first full 3-D structural study of any long, non-coding RNA (lncRNA) ...
Read More »Dermtech’s lncRNA-based pigmented lesion assay (pla) receives medicare coverage
DermTech, Inc., a leader in precision dermatology enabled by a non-invasive skin genomics platform, announced today that the Medicare Administrative...
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