A postdoctoral position is available for a highly-motivated candidate to study mechanisms of hepatic stellate cell biology and liver fibrosis in the Mullen Laboratory in the Gastrointestinal Unit at Massachusetts General Hospital and Harvard Medical School. The candidate will lead projects to understand how long noncoding RNAs and protein-coding genes regulate hepatic stellate activity and liver fibrosis using both tissue culture and mouse models. The lab uses both genetic and biochemical approaches to study RNA function, including antisense oligonucleotides for RNA depletion, modification of the genome using CRISPR technology, and tagging RNAs for precipitation.
Successful candidates will have earned a Ph.D. in genetics, molecular biology, cellular biology, or related fields and demonstrated the ability to complete research projects independently. A background in research related to fibrosis or experience with mouse models will strengthen the application. The candidate must also demonstrate proficient oral and written communication skills and the enthusiasm to work in a multidisciplinary and collaborative environment.
The focus of this project is on liver disease, but the candidate will also interact with team of investigators who study fibrosis across multiple organ systems.
Qualifications
Interested candidates should send a curriculum vitae, a brief description of research interests, and the contact information and three letters of recommendation to:
Alan C. Mullen, MD, PhD
GI Unit
Massachusetts General Hospital
acmullen@mgh.harvard.edu (subject line: postdoc position – fibrosis)
Additional information about the lab can be found at: mullenlab.mgh.harvard.edu