Tag Archives: BRCA2

Featured long non-coding RNA - PCAT-1

Impairment of double-stranded DNA break (DSB) repair is essential to many cancers. However, although mutations in DSB repair proteins are common in hereditary cancers, mechanisms of impaired DSB repair in sporadic cancers remain incompletely understood. Here, a team led by researchers at the Michigan Center for Translational Pathology describes the first role for a long noncoding RNA (lncRNA) in DSB ...

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