Of the approximately 10,000 long noncoding (lnc) RNAs encoded in the human genome, the functions of only a few have been characterized. Mounting evidence suggests that long noncoding RNAs (lncRNAs) can function as microRNA sponges and compete for microRNA binding to protein-coding transcripts. However, the prevalence, functional significance and targets of lncRNA-mediated sponge regulation of cancer are mostly unknown. Here, ...
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